Extended Spectrum Beta-Lactamase Resistant (ESBLR) Enterobacteriaceae

Extended Spectrum Isn’t a Bigger Rainbow

Extended spectrum in this case refers to the fact that some bacteria have developed resistance against a broad group of antibiotics including those that as little as 10 or so years ago had no noted resistance at all.  This type of extended spectrum resistance is also found in species that are not members of the Enterobacteriaceae family.  The detailed classifications of the varying types and mechanisms of specific resistance is a highly technical issue best reserved for experts in the field.  If you are personally concerned about these types of infections, please consult your physician who is the best source of information about the specific medications prescribed to you or your family.

Penicillin Structure

Antibiotic Basics

The correct and consistent use of antibiotics can go a long way toward limiting the spread of existing resistance patterns as well as toward preventing the further development of additional resistance.  Only take antibiotics when prescribed to you by a licensed physician and never give you medication to others, nor take medications prescribed for someone else.  Always use the medication EXACTLY as instructed and always take all of it even if you feel better before the course prescribed to you is finished.  Do not order antibiotics over the Internet without a physician’s authorization!  Remember that antibiotics are only effective against bacteria and will make absolutely difference in viral infections, which cause the majority of respiratory illnesses.  Encourage your physician to be sparing in the use of antibiotics, and to be certain that bacteria are actually causing the illness.  Competent and timely microbiological testing can and will identify bacterial causes of infection and will also indicate the best antibiotic to use to treat such infections.  These types of microbiological testing can also readily identify ESBLR infections and can also identify potential treatments that may be effective if you are unfortunate enough to acquire such an infection.  This testing must be ordered by a physician and you should encourage your physician to have such tests performed as part of your care to ensure accurate diagnosis and treatment.

ESBLR  2

ESBLR Summary

The whole issue can be best easily summarized as a being a group of bacteria that have resistance against a wide range of antibiotics, rendering some of the infections they cause essentially untreatable.  Avoiding infection with these organisms is therefore very important.  The extended spectrum resistance in most commonly found in isolates of E. coli and Klebsiella sp, especially K. pneumoniae.  However, other members of the Enterobacteriaceae family could demonstrate such resistance over time as the trend develops.

ESBLR Res

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